Manuel Uribe: Lost almost 1000 pounds
Uribe drew worldwide attention when he appeared on the Televisa television network in January 2006, but turned down offers for gastric surgery in Italy. In March 2007, Uribe set a goal to lower his weight to 120 kg (265 lb). He has also been featured on "World's Heaviest Man", a television documentary about his bedridden life and attempts to lose weight. By the end of 2008, Uribe had reduced his weight to 360 kg (800 lb). His weight loss efforts continue to this day.
David Smith: Lost 400 pounds and became a personal trainer
Rosalie Bradford: Guinness World Record for most weight lost by a woman
Sadly enough, in one of the five sessions of surgery to remove excess skin during her weight loss, she had some complications that later caused her death. She died on November 29, 2006 at a hospital in Lakeland at the age of 63. Rosalie Bradford posthumously continues to hold the world record for having lost the most weight.
John Stone: Wanted to lose his beer belly and became a bodybuilder
Rob Cooper: lost 300 pounds in 2 years
He began weight training and put on over 50 pounds of muscle in the years since, lowering his body fat even further. Residing in Canada, Rob is now healthy, muscular, and follows a healthy eating plan and exercise routine.
Jon Brower Minnoch: Lost 22kg per month
After following a strict diet plan, Jon Brower Minnoch (USA), reduced to 216 kg (34 st) by July 1979, thus indicating a weight loss of at least 419 kg (66 st) in 16 months. This averages at 22.05 kg (3 st 9 lbs or 57.75 lbs) a month!
The diet consisted of just 1,200 calories a day. Sadly, though, by October 1981, the former taxi driver had put on over 89 kg (34 st), undoing all his good work. Jon Brower Minnoch passed away on September 10, 1983 weighing 362 kilograms or 796 pounds.
Michael Hebranko: former heaviest man on earth down seized to 90 kg
After a stay at the St. Luke’s Hospital in New York, he dropped his weight from 411 kg (910 lb) to 90 kg (200 lb) and waist size from 290 cm (110 in) to 91 cm (36 in) in 19 months with the help of the dieting and exercise coach Richard Simmons and was recorded in the Guinness Book of World Records for the highest recorded weight loss in 1990. He lost some of this weight from surgical removal of fat. He then toured the United States lecturing about his experiences and advocating dieting and exercise and appeared in infomercials promoting Richard Simmons.
However, seven years later, he gained up to 453 kg (1,000 lb) and had to be repeatedly hospitalized to the Brookhaven Rehabilitation and Health Care Center. In June 1999, Hebranko was at his peak weight of 500 kg (1,100 lb).
Steve Vaught: Started a cross country walk to lose weight
Apart from attracting his fair share of media attention, he managed to shed over 100 lb in the process. But Vaught's journey was not without controversy. Questions were raised by both the media and fans as to whether Vaught caught rides and did not in fact walk every mile. Vaught was also still morbidly obese upon completion of his journey. In his defense he claims "You can't cheat. There is no possible way to cheat. It was my journey (…) I didn't care about where I was at and where I was going. I don't care if it was 2,800 or 1,500 miles. . . . It's about where your head is."
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